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Targets Recommended: Akt

1

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8969 API-1

NSC177223

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
API-1 (NSC-177223) 是Akt/PKB 抑制剂,可同 PH 结构域相结合并抑制 Akt 膜易位,有效降低 Akt 的磷酸化水平。它可选择性的抑制PKB,对 PKC 和 PKA 的激活无抑制作用。它可以和 TNF 相关的凋亡诱导配体协同作用从而诱导细胞凋亡。

化合物

API-1
Cat.No: T8969
Synonym: NSC177223
Target: Akt
Cat. No. Product Name Species Expression System
TMPY-01176 cIAP1 Protein, Human, Recombinant (Avi)

Hiap-2,API1,HIAP2,RNF48,baculoviral IAP re...

Human E. coli
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP repeats (BIRs). The BIR domains of cIAP1 and cIAP2 bind to caspases, the key effector proteases of apoptosis. The IAP protein family which can enhance cell survival are crucial regulators of programmed cell death. Both cIAP1 and cIAP2 are the E3 ubiquitin protein isopeptide ligase...

重组蛋白

cIAP1 Protein, Human, Recombinant (Avi)
Cat.No: TMPY-01176
Species: Human
Expression System: E. coli
TargetMol Loading
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